Cuproptosis-related molecular subtypes direct T cell exhaustion phenotypes and therapeutic strategies for patients with lung adenocarcinoma

Cuproptosis-related molecular subtypes direct T cell exhaustion phenotypes and therapeutic strategies for patients with lung adenocarcinoma

Background: T cell exhaustion (TEX) heterogeneity leads to unfavorable immunotherapeutic responses in patients with cancer. Classification of TEX molecular phenotypes is pivotal to overcoming TEX and improving immunotherapies in the clinical setting. Cuproptosis is a novel form of programmed cell de...

Full description

Bibliographic Details
Main Authors: Yi-Pan Zhu, Hui-Ting Deng, Xiuyu Wang, Michal A. Rahat, Shupeng Sun, Qiang-Zhe Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pharmacology
Subjects:
cuproptosis
T cell exhaustion
tumor immune microenvironment
lung adenocarcinoma
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1146468/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1146468/full

Similar Items