Synthesis of Fluorinated Nucleosides/Nucleotides and Their Antiviral Properties

The FDA has approved several drugs based on the fluorinated nucleoside pharmacophore, and numerous drugs are currently in clinical trials. Fluorine-containing nucleos(t)ides offer significant antiviral and anticancer activity. The insertion of a fluorine atom, either in the base or sugar of nucleos(...

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Bibliographic Details
Main Authors: Yugandhar Kothapalli, Ransom A. Jones, Chung K. Chu, Uma S. Singh
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/10/2390