Flexibility and Function of Distal Substrate-Binding Tryptophans in the Blue Mussel β-Mannanase <i>Me</i>Man5A and Their Role in Hydrolysis and Transglycosylation

Flexibility and Function of Distal Substrate-Binding Tryptophans in the Blue Mussel β-Mannanase <i>Me</i>Man5A and Their Role in Hydrolysis and Transglycosylation

β-Mannanases hydrolyze β-mannans, important components of plant and microalgae cell walls. Retaining β-mannanases can also catalyze transglycosylation, forming new β-mannosidic bonds that are applicable for synthesis. This study focused on the blue mussel (<i>Mytilus edulis</i>) GH5_10 β...

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Bibliographic Details
Main Authors: Simon Birgersson, Johan Morrill, Olof Stenström, Mathias Wiemann, Ulrich Weininger, Pär Söderhjelm, Mikael Akke, Henrik Stålbrand
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Catalysts
Subjects:
β-mannanase
enzymatic synthesis
transglycosylation
flexibility
novel glycosides
Online Access:https://www.mdpi.com/2073-4344/13/9/1281

Internet

https://www.mdpi.com/2073-4344/13/9/1281

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