Fibroblastic reticular cells mitigate acute GvHD via MHCII-dependent maintenance of regulatory T cells
Acute graft versus host disease (aGvHD) is a life-threatening complication of allogeneic hematopoietic cell transplantation (allo-HCT) inflicted by alloreactive T cells primed in secondary lymphoid organs (SLOs) and subsequent damage to aGvHD target tissues. In recent years, Treg transfer and/or exp...
Principais autores: | , , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
American Society for Clinical investigation
2022-11-01
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coleção: | JCI Insight |
Assuntos: | |
Acesso em linha: | https://doi.org/10.1172/jci.insight.154250 |