Novel Prodrugs for Targeting Diagnostic and Therapeutic Radionuclides to Solid Tumors

Novel Prodrugs for Targeting Diagnostic and Therapeutic Radionuclides to Solid Tumors

Most cancer therapeutics (chemo, radiation, antibody-based, anti-angiogenic)are at best partially and/or temporarily effective. In general, the causes for failure can besummarized as: (i) poor diffusion and/or nonuniform distribution of drug/prodrugmolecules in solid tumors; (ii) high drug concentra...

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Bibliographic Details
Main Authors: S. James Adelstein, Pavel Pospisil, Ketai Wang, Houari Korideck, Amin I. Kassis
Format: Article
Language:English
Published: MDPI AG 2008-02-01
Series:Molecules
Subjects:
Prodrug
solid tumors
radioiodine
radioimaging
radiotherapy
Online Access:http://www.mdpi.com/1420-3049/13/2/391/

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http://www.mdpi.com/1420-3049/13/2/391/

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