Chromosome structural variation in tumorigenesis: mechanisms of formation and carcinogenesis

Abstract With the rapid development of next-generation sequencing technology, chromosome structural variation has gradually gained increased clinical significance in tumorigenesis. However, the molecular mechanism(s) underlying this structural variation remain poorly understood. A search of the lite...

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Bibliographic Details
Main Authors: Wen-Jun Wang, Ling-Yu Li, Jiu-Wei Cui
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13072-020-00371-7