Unfolded Protein Response Pathways Correlatively Modulate Endoplasmic Reticulum Stress Responses in Rat Retinal Müller Cells

Background. Endoplasmic reticulum stress (ERS) in the retinal Müller cells is a key factor contributing to the retinal inflammation and vascular leakage in diabetic retinopathy (DR). This study was to investigate the underlying mechanisms through which the 3 main unfolded protein response (UPR) path...

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Bibliographic Details
Main Authors: Shengyu Wu, Xiaolu Zhu, Biechuan Guo, Tian Zheng, Jiangbo Ren, Wen Zeng, Xiaomin Chen, Min Ke
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/9028483