RAFT-Derived Polymethacrylates as a Superior Treatment for Recurrent Vulvovaginal Candidiasis by Targeting Biotic Biofilms and Persister Cells

RAFT-Derived Polymethacrylates as a Superior Treatment for Recurrent Vulvovaginal Candidiasis by Targeting Biotic Biofilms and Persister Cells

BackgroundVulvovaginal candidiasis (VVC) is a common infection in need of more effective treatment. Formation of epithelium-associated Candida biofilms and the presence of persister cells are among the major contributing factors to the recurrence of this condition. We have previously developed RAFT-...

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Bibliographic Details
Main Authors: Xueqing Wu, Sisi Zhang, Xinxin Xu, Laien Shen, Boyun Xu, Wenzhen Qu, Wenyi Zhuang, Katherine Locock, Margaret Deighton, Yue Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
RVVC
mouse model
antifungal treatment
RAFT-derived polymethacrylates
biotic biofilms
persister cells
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02592/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02592/full

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