Regulation of Life & Death by REGγ

REGγ, a proteasome activator belonging to the 11S (otherwise known as REG, PA28, or PSME) proteasome activator family, is widely present in many eukaryotes. By binding to the 20S catalytic core particle, REGγ acts as a molecular sieve to selectively target proteins for degradation in an ATP- and ubi...

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Bibliographic Details
Main Authors: Keaton E. Funderburk, Jungseog Kang, Henry J. Li
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/15/2281