High-dimensional analysis of T-cell profiling variations following belimumab treatment in systemic lupus erythematosus

High-dimensional analysis of T-cell profiling variations following belimumab treatment in systemic lupus erythematosus

Objective This study sought to elucidate the molecular impacts of belimumab (BEL) treatment on T-cell immune profiling in SLE.Methods We used mass cytometry with 25 marker panels for T-cell immune profiling in peripheral blood T cells (CD3+) from 22 patients with BEL-treated SLE and 20 controls with...

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Bibliographic Details
Main Authors: Hiroya Hashimoto, Akio Niimi, Shinji Maeda, Tomoyo Maeda, Shin-ya Tamechika, Shuntaro Isogai, Taio Naniwa
Format: Article
Language:English
Published: BMJ Publishing Group 2023-08-01
Series:Lupus Science and Medicine
Online Access:https://lupus.bmj.com/content/10/2/e000976.full

Internet

https://lupus.bmj.com/content/10/2/e000976.full

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