Conformational Dynamics of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

Conformational Dynamics of the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

Variants of SARS-CoV-2 keep emerging and causing new waves of COVID-19 around the world. Effective new approaches in drug development are based on the binding of agents, such as neutralizing monoclonal antibodies to a receptor-binding domain (RBD) of SARS-CoV-2 spike protein. However, mutations in R...

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Bibliographic Details
Main Authors: Aleksandra A. Mamchur, Tatiana B. Stanishneva-Konovalova, Yuliana A. Mokrushina, Viktoria A. Abrikosova, Yu Guo, Hongkai Zhang, Stanislav S. Terekhov, Ivan V. Smirnov, Igor A. Yaroshevich
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
COVID-19
SARS-CoV-2
receptor-binding domain
molecular dynamics
Online Access:https://www.mdpi.com/2227-9059/10/12/3233

Internet

https://www.mdpi.com/2227-9059/10/12/3233

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