Modeling the Homologous Recombination Process: Methods, Successes and Challenges

Modeling the Homologous Recombination Process: Methods, Successes and Challenges

Homologous recombination (HR) is a fundamental process common to all species. HR aims to faithfully repair DNA double strand breaks. HR involves the formation of nucleoprotein filaments on DNA single strands (ssDNA) resected from the break. The nucleoprotein filaments search for homologous regions i...

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Bibliographic Details
Main Authors: Afra Sabei, Mara Prentiss, Chantal Prévost
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
molecular modeling
molecular dynamics simulations
homologous recombination
DNA stretching
RecA
protein filament
Online Access:https://www.mdpi.com/1422-0067/24/19/14896

Internet

https://www.mdpi.com/1422-0067/24/19/14896

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