Stepwise PEG synthesis featuring deprotection and coupling in one pot
The stepwise synthesis of monodisperse polyethylene glycols (PEGs) and their derivatives usually involves using an acid-labile protecting group such as DMTr and coupling the two PEG moieties together under basic Williamson ether formation conditions. Using this approach, each elongation of PEG is ac...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Beilstein-Institut
2021-12-01
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Series: | Beilstein Journal of Organic Chemistry |
Subjects: | |
Online Access: | https://doi.org/10.3762/bjoc.17.207 |