Stepwise PEG synthesis featuring deprotection and coupling in one pot

The stepwise synthesis of monodisperse polyethylene glycols (PEGs) and their derivatives usually involves using an acid-labile protecting group such as DMTr and coupling the two PEG moieties together under basic Williamson ether formation conditions. Using this approach, each elongation of PEG is ac...

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Bibliographic Details
Main Authors: Logan Mikesell, Dhananjani N. A. M. Eriyagama, Yipeng Yin, Bao-Yuan Lu, Shiyue Fang
Format: Article
Language:English
Published: Beilstein-Institut 2021-12-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.17.207