The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication

The glycoprotein 5 of porcine reproductive and respiratory syndrome virus stimulates mitochondrial ROS to facilitate viral replication

ABSTRACTViruses have evolved sophisticated mechanisms to manipulate host cell organelles to serve as niches for persistence and proliferation. In the present study, we aimed to investigate the role of cellular organelles in the replication of porcine reproductive and respiratory syndrome virus (PRRS...

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Bibliographic Details
Main Authors: Shuang Zhang, Lei Zeng, Bing-Qian Su, Guo-Yu Yang, Jiang Wang, Sheng-Li Ming, Bei-Bei Chu
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
PRRSV
ER-mitochondria contacts
IP3R
VDAC1
autophagy
NLRP3 inflammasome
Online Access:https://journals.asm.org/doi/10.1128/mbio.02651-23

Internet

https://journals.asm.org/doi/10.1128/mbio.02651-23

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