Modelling of p-tyramine transport across human intestinal epithelial cells predicts the presence of additional transporters

p-Tyramine (TYR) is an endogenous trace amine, which can also be synthesized by intestinal microbiota, and is present in commonly consumed diets. TYR is an agonist for the intracellular trace amine-associated receptor 1, which has been implicated in psychiatric, metabolic, and immune-related disorde...

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Bibliographic Details
Main Authors: Shreyasi Sarkar, Ivan Saika-Voivod, Mark D. Berry
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.1009320/full