Synthesis and Anticholinesterase Evaluation of Cassine, Spectaline and Analogues

In this work, twelve analogues of piperidine alkaloids (-)-cassine and (-)-spectaline were synthesized, as well as the racemic forms of these natural products. The compounds were evaluated for their inhibition of electric eel acetylcholinesterase (AChE<sub>ee</sub>) and human butyrylchol...

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Bibliographic Details
Main Authors: Marcela C. R. Silva, Adriana F. L. Vilela, Carmen L. Cardoso, Ronaldo A. Pilli
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Scientia Pharmaceutica
Subjects:
Online Access:https://www.mdpi.com/2218-0532/90/4/63