Recovery and activation of hydroxymethylglutaryl coenzyme A reductase from rat small intestine.

We describe a method for estimating the total activity of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase (EC 1.1.1.34) in the small intestine of rats. An homogenate of the whole small intestine is prepared rapidly and assayed directly to maximize the yield of enzyme and to minimize opportunity f...

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Bibliographic Details
Main Authors: N L Young, C D Saudek, S A Crawford, S L Zuckerbrod
Format: Article
Language:English
Published: Elsevier 1982-02-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520381566