Multiplex detection of homo- and heterodimerization of g protein-coupled receptors by proximity biotinylation.

Dimerization of G protein-coupled receptors (GPCRs) represents a potential mechanism by which GPCR functions are regulated. Several resonance energy transfer (RET)-based methods have revealed GPCR homo- and heterodimerization. However, interpretation of an increase in FRET efficiency could be attrib...

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Bibliographic Details
Main Authors: Elisabeth Steel, Victoria L Murray, Allen P Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3972117?pdf=render