AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage

AQP2 Promotes Astrocyte Activation by Modulating the TLR4/NFκB-p65 Pathway Following Intracerebral Hemorrhage

Microglial and astrocyte activation and related cytokine secretion play key roles in secondary brain injury following intracerebral hemorrhage (ICH). We assessed the role of aquaporin (AQP)2 in immune response after ICH. We prospectively collected data from 33 patients with ICH and analyzed the seru...

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Bibliographic Details
Main Authors: Shuwen Deng, Xiqian Chen, Qiang Lei, Wei Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
aquaporin-2
intracerebral hemorrhage
microglial
astrocyte
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.847360/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.847360/full

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