α-Synuclein Fibrils as Penrose Machines: A Chameleon in the Gear

In 1957, Lionel Penrose built the first man-made self-replicating mechanical device and illustrated its function in a series of machine prototypes, prefiguring our current view of the genesis and the proliferation of amyloid fibrils. He invented and demonstrated, with the help of his son Roger, the...

Full description

Bibliographic Details
Main Authors: Francesca De Giorgi, Vladimir N. Uversky, François Ichas
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/12/4/494