Membrane Sphingomyelin in Host Cells Is Essential for Nucleocapsid Penetration into the Cytoplasm after Hemifusion during Rubella Virus Entry

Membrane Sphingomyelin in Host Cells Is Essential for Nucleocapsid Penetration into the Cytoplasm after Hemifusion during Rubella Virus Entry

ABSTRACT The lipid composition of the host cell membrane is one of the key determinants of the entry of enveloped viruses into cells. To elucidate the detailed mechanisms behind the cell entry of rubella virus (RuV), one of the enveloped viruses, we searched for host factors involved in such entry b...

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Bibliographic Details
Main Authors: Yoshio Mori, Masafumi Sakata, Shota Sakai, Toru Okamoto, Yuichiro Nakatsu, Shuhei Taguwa, Noriyuki Otsuki, Yusuke Maeda, Kentaro Hanada, Yoshiharu Matsuura, Makoto Takeda
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
rubella virus
fusion
hemifusion
sphingomyelin
CRISPR/Cas9
membrane fusion
Online Access:https://journals.asm.org/doi/10.1128/mbio.01698-22

Internet

https://journals.asm.org/doi/10.1128/mbio.01698-22

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