Rhubarb ameliorates cognitive dysfunction in a rat model of Alzheimer's disease through regulation of the intestinal microbiome

Objective: To determine the mechanism whereby rhubarb (Rheum tanguticum MAXIM. Ex BALF.) may ameliorate cognitive dysfunction through regulation of the intestinal microbiome. Methods: We used a rat model of human microbiome-associated (HMA)-AD to characterize the therapeutic effect of rhubarb on cog...

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Bibliographic Details
Main Authors: Huizhen Zhao, Demin Gao, Xiaoyan Gao
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Traditional Chinese Medical Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754819300961