Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice

Intra-hippocampal cis-P tau microinjection induces long-term changes in behavior and synaptic plasticity in mice

Abstract Background Alzheimer's disease is accompanied by an abnormal high accumulation of cis-P tau. However, the long-term changes in behavior following tau accumulation remains under debate. The present study investigated the long-term effects of tauopathy on learning and memory, synaptic pl...

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Bibliographic Details
Main Authors: Bakhtiarzadeh Fatemeh, Shahpasand Koorosh, Shojaei Amir, Fathollahi Yaghoub, Mirnajafi-Zadeh Javad
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Behavioral and Brain Functions
Subjects:
Alzheimer’s like disease
Cis P-tau
Dorsal and ventral hippocampus
Learning and memory and synaptic plasticity
Online Access:https://doi.org/10.1186/s12993-023-00211-0

Internet

https://doi.org/10.1186/s12993-023-00211-0

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