Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans.
BACKGROUND: Acute respiratory distress syndrome (ARDS) is a devastating complication of numerous underlying conditions, most notably sepsis. Although pathologic vascular leak has been implicated in the pathogenesis of ARDS and sepsis-associated lung injury, the mechanisms promoting leak are incomple...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2006-01-01
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Series: | PLoS Medicine |
Online Access: | http://dx.doi.org/10.1371/journal.pmed.0030046 |