Excess Circulating Angiopoietin-2 May Contribute to Pulmonary Vascular Leak in Sepsis in Humans.

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a devastating complication of numerous underlying conditions, most notably sepsis. Although pathologic vascular leak has been implicated in the pathogenesis of ARDS and sepsis-associated lung injury, the mechanisms promoting leak are incomple...

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Bibliographic Details
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-01-01
Series:PLoS Medicine
Online Access:http://dx.doi.org/10.1371/journal.pmed.0030046