Analysis of circRNAs and circRNA-associated competing endogenous RNA networks in β-thalassemia

Abstract The involvement of circRNAs in β-thalassemia and their actions on fetal hemoglobin (HbF) is unclear. Here, the circRNAs in β-thalassemia carriers with high HbF levels were comprehensively analyzed and compared with those of healthy individuals. Differential expression of 2183 circRNAs was o...

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Bibliographic Details
Main Authors: Fang Yang, Heyun Ruan, Shuquan Li, Wei Hou, Yuling Qiu, Lingjie Deng, Sha Su, Ping Chen, Lihong Pang, Ketong Lai
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-12002-0