Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models
Summary: The inner ear of humans and large animals is embedded in a thick and dense bone that makes dissection challenging. Here, we present a protocol that enables three-dimensional (3D) characterization of intact inner ears from large-animal models. We describe steps for decalcifying bone, using s...
Main Authors: | Adele Moatti, Yuheng Cai, Chen Li, Kristen D. Popowski, Ke Cheng, Frances S. Ligler, Alon Greenbaum |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | STAR Protocols |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166723001788 |
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