Superhelical destabilization in regulatory regions of stress response genes.

Stress-induced DNA duplex destabilization (SIDD) analysis exploits the known structural and energetic properties of DNA to predict sites that are susceptible to strand separation under negative superhelical stress. When this approach was used to calculate the SIDD profile of the entire Escherichia c...

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Bibliographic Details
Main Authors: Huiquan Wang, Craig J Benham
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2211533?pdf=render