Circulating Trimethylamine N-Oxide Is Associated with Increased Risk of Cardiovascular Mortality in Type-2 Diabetes: Results from a Dutch Diabetes Cohort (ZODIAC-59)

Circulating Trimethylamine N-Oxide Is Associated with Increased Risk of Cardiovascular Mortality in Type-2 Diabetes: Results from a Dutch Diabetes Cohort (ZODIAC-59)

Trimethylamine N-oxide (TMAO), a novel cardiovascular (CV) disease and mortality risk marker, is a gut microbiota-derived metabolite as well. Recently, plasma concentrations of branched-chain amino acids (BCAA) have been reported to be affected by microbiota. The association of plasma TMAO with CV m...

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Bibliographic Details
Main Authors: Jose L. Flores-Guerrero, Peter R. van Dijk, Margery A. Connelly, Erwin Garcia, Henk J. G. Bilo, Gerjan Navis, Stephan J. L. Bakker, Robin P. F. Dullaart
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Clinical Medicine
Subjects:
biomarker
BCAA
cardiovascular disease
trimethylamine-N-oxide
TMAO
type 2 Diabetes
Online Access:https://www.mdpi.com/2077-0383/10/11/2269

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https://www.mdpi.com/2077-0383/10/11/2269

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