A novel therapeutic approach for inflammatory bowel disease by exosomes derived from human umbilical cord mesenchymal stem cells to repair intestinal barrier via TSG-6

A novel therapeutic approach for inflammatory bowel disease by exosomes derived from human umbilical cord mesenchymal stem cells to repair intestinal barrier via TSG-6

Abstract Background Exosomes as the main therapeutic vectors of mesenchymal stem cells (MSC) for inflammatory bowel disease (IBD) treatment and its mechanism remain unexplored. Tumor necrosis factor-α stimulated gene 6 (TSG-6) is a glycoprotein secreted by MSC with the capacities of tissue repair an...

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Bibliographic Details
Main Authors: Shaopeng Yang, Xiaonan Liang, Jia Song, Chenyang Li, Airu Liu, Yuxin Luo, Heran Ma, Yi Tan, Xiaolan Zhang
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Inflammatory bowel disease
Mesenchymal stem cells
Exosome
Tumor necrosis factor-α-stimulated gene 6
Intestinal barrier
Online Access:https://doi.org/10.1186/s13287-021-02404-8

Internet

https://doi.org/10.1186/s13287-021-02404-8

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