Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase

Baicalein, 7,8-Dihydroxyflavone and Myricetin as Potent Inhibitors of Human Ornithine Decarboxylase

Background: Human ornithine decarboxylase (ODC) is a well-known oncogene, and the discovery of ODC enzyme inhibitors is a beneficial strategy for cancer therapy and prevention. Methods: We examined the inhibitory effects of a variety of flavone and flavonol derivatives on ODC enzymatic activity, and...

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Bibliographic Details
Main Authors: Yun-Chin Liu, Yi-Liang Liu, Ju-Yi Hsieh, Chang-Hsu Wang, Chi-Li Lin, Guang-Yaw Liu, Hui-Chih Hung
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nutrients
Subjects:
ornithine decarboxylase
chemoprevention
molecular docking simulations: baicalein
7,8-dihydroxyflavone
myricetin
Online Access:https://www.mdpi.com/2072-6643/12/12/3867

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https://www.mdpi.com/2072-6643/12/12/3867

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