Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection

Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection

Innate lymphoid cells (ILC) are involved with different immune responses. Here the authors show that Interferon regulatory factor 1 (IRF1) is important for intestinal ILC3 accumulation during Citrobacter rodentium infection and promotes release of the protective cytokine IL-22 and response to IL-23.

Bibliographic Details
Main Authors: Angelika Schmalzl, Tamara Leupold, Lucas Kreiss, Maximilian Waldner, Sebastian Schürmann, Markus F. Neurath, Christoph Becker, Stefan Wirtz
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-33326-5

Internet

https://doi.org/10.1038/s41467-022-33326-5

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