Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Background: Polycystic kidney disease (PKD) is a genetic disorder affecting millions of people worldwide that is characterized by fluid-filled cysts and leads to end-stage renal disease (ESRD). The hallmarks of PKD are proliferation and dedifferentiation of tubular epithelial cells, cellular process...

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Bibliographic Details
Main Authors: Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman D. Bülow, Tiffany Migeon, Sandrine Placier, Christos E. Chadjichristos, Peter Boor, Christos Chatziantoniou
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Notch3
polycystic kidney disease
renal cell carcinoma
renal fibrosis
chronic kidney disease
renal inflammation
Online Access:https://www.mdpi.com/1422-0067/23/2/884

Internet

https://www.mdpi.com/1422-0067/23/2/884

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