Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Activation of Notch3 in Renal Tubular Cells Leads to Progressive Cystic Kidney Disease

Background: Polycystic kidney disease (PKD) is a genetic disorder affecting millions of people worldwide that is characterized by fluid-filled cysts and leads to end-stage renal disease (ESRD). The hallmarks of PKD are proliferation and dedifferentiation of tubular epithelial cells, cellular process...

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Bibliographic Details
Main Authors:	Sonja Djudjaj, Panagiotis Kavvadas, Niki Prakoura, Roman D. Bülow, Tiffany Migeon, Sandrine Placier, Christos E. Chadjichristos, Peter Boor, Christos Chatziantoniou
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	International Journal of Molecular Sciences
Subjects:	Notch3 polycystic kidney disease renal cell carcinoma renal fibrosis chronic kidney disease renal inflammation
Online Access:	https://www.mdpi.com/1422-0067/23/2/884

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