Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies

Selenazolyl-hydrazones as Novel Selective MAO Inhibitors With Antiproliferative and Antioxidant Activities: Experimental and In-silico Studies

The novel approach in the treatment of complex multifactorial diseases, such as neurodegenerative disorders and cancer, requires a development of efficient multi-targeting oriented drugs. Since oxidative stress significantly contributes to the pathogenesis of cancer and neurodegenerative disorders,...

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Bibliographic Details
Main Authors: Hana Elshaflu, Tamara R. Todorović, Milan Nikolić, Aleksandar Lolić, Aleksandar Višnjevac, Stefanie Hagenow, José M. Padrón, Alfonso T. García-Sosa, Ivana S. Djordjević, Sonja Grubišić, Holger Stark, Nenad R. Filipović
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Chemistry
Subjects:
selenazoles
MAO B
Anticancer activity
Docking
Antioxidant agents
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00247/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00247/full

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