Structure of nucleosome-bound human PBAF complex

BAF and PBAF are SWI/SNF family chromatin remodeling complexes that create nucleosome-depleted regions for transcription activation. Here the authors report the structure of a 13-subunit human PBAF in complex with acetylated nucleosome in ADP-BeF3-bound state that provides structural insights into P...

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Bibliographic Details
Main Authors: Li Wang, Jiali Yu, Zishuo Yu, Qianmin Wang, Wanjun Li, Yulei Ren, Zhenguo Chen, Shuang He, Yanhui Xu
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34859-5