Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting.

Safety and feasibility of an in situ vaccination and immunomodulatory targeted radionuclide combination immuno-radiotherapy approach in a comparative (companion dog) setting.

<h4>Rationale</h4>Murine syngeneic tumor models have revealed efficacious systemic antitumor responses following primary tumor in situ vaccination combined with targeted radionuclide therapy to secondary or metastatic tumors. Here we present studies on the safety and feasibility of this...

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Bibliographic Details
Main Authors: Kara Magee, Ian R Marsh, Michelle M Turek, Joseph Grudzinski, Eduardo Aluicio-Sarduy, Jonathan W Engle, Ilene D Kurzman, Cindy L Zuleger, Elizabeth A Oseid, Christine Jaskowiak, Mark R Albertini, Karla Esbona, Bryan Bednarz, Paul M Sondel, Jamey P Weichert, Zachary S Morris, Reinier Hernandez, David M Vail
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0255798

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https://doi.org/10.1371/journal.pone.0255798

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