Microparticle-Induced Coagulation Relates to Coronary Artery Atherosclerosis in Severe Aortic Valve Stenosis.

Microparticle-Induced Coagulation Relates to Coronary Artery Atherosclerosis in Severe Aortic Valve Stenosis.

Circulating microparticles (MPs) derived from endothelial cells and blood cells bear procoagulant activity and promote thrombin generation. Thrombin exerts proinflammatory effects mediating the progression of atherosclerosis. Aortic valve stenosis may represent an atherosclerosis-like process involv...

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Bibliographic Details
Main Authors: Patrick Horn, Gülsüm Erkilet, Verena Veulemans, Patric Kröpil, Leon Schurgers, Tobias Zeus, Christian Heiss, Malte Kelm, Ralf Westenfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807100?pdf=render

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http://europepmc.org/articles/PMC4807100?pdf=render

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