Ablation of Peroxiredoxin V Exacerbates Ischemia/Reperfusion-Induced Kidney Injury in Mice

Ischemia/reperfusion (I/R) is one of the major causes of acute kidney injury (AKI) and associated with increased mortality and progression to chronic kidney injury (CKI). Molecular mechanisms underlying I/R injury involve the production and excessive accumulation of reactive oxygen species (ROS). Pe...

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Bibliographic Details
Main Authors: Jiyoung Park, Eun Gyeong Lee, Ho Jin Yi, Nam Hee Kim, Sue Goo Rhee, Hyun Ae Woo
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/9/8/769