Screening of active constituents in traditional Chinese medicines as potential Salmonella Typhimurium virulence inhibitors targeting Salmonella pathogenicity island III

Screening of active constituents in traditional Chinese medicines as potential Salmonella Typhimurium virulence inhibitors targeting Salmonella pathogenicity island III

Objective: To screen active constituents of traditional Chinese medicines (TCMs) as potential virulence inhibitors of Salmonella pathogenicity island III (SPI-3). Methods: The potential binding of TCM constituents to the MgtC protein of SPI-3 was clarified using molecular docking. The β-galactosidas...

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Bibliographic Details
Main Authors: Mengdi Cui, Ou Tao, Yuanyuan Wang, Yulei Yang, Sufen Miao, Junling Hou, Xiaopeng Deng, Meng Shen, Shanshan Jia, Mei Zhang
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Salmonella Typhimurium
Virulence inhibitor
Salmonella pathogenicity island III
mgtC
Traditional Chinese medicine constituent
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754823000534

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http://www.sciencedirect.com/science/article/pii/S2095754823000534

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