Downregulation of m6A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness

Downregulation of m6A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness

N6‐methyladenosine (m6A) and its regulatory proteins have been associated with tumorigenesis in several cancer types. However, knowledge on the mechanistic network related to m6A in bladder cancer (BlCa) is rather limited, requiring further investigation of its functional role. We aimed to uncover t...

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Bibliographic Details
Main Authors: Catarina Guimarães‐Teixeira, João Lobo, Vera Miranda‐Gonçalves, Daniela Barros‐Silva, Cláudia Martins‐Lima, Sara Monteiro‐Reis, José Pedro Sequeira, Isa Carneiro, Margareta P. Correia, Rui Henrique, Carmen Jerónimo
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:Molecular Oncology
Subjects:
bladder cancer
epitranscriptome
m6A‐regulators proteins
METTL14
N6‐methyladenosine
RNA modifications
Online Access:https://doi.org/10.1002/1878-0261.13181

Internet

https://doi.org/10.1002/1878-0261.13181

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