Inhibitory effect of apigenin on AK23-induced desmoglein3 depletion in HaCaT cell model of pemphigus vulgaris via suppression of p38 MAPK phosphorylation

Inhibitory effect of apigenin on AK23-induced desmoglein3 depletion in HaCaT cell model of pemphigus vulgaris via suppression of p38 MAPK phosphorylation

This study aimed to investigate the effect of apigenin, a flavonoid widely distributed in plants, on AK23-induced desmoglein3 (Dsg3) depletion in pemphigus vulgaris (PV) model using HaCaT cells. Dispase-based dissociation assay showed that the number of cell fragments, which increased compared to th...

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Bibliographic Details
Main Authors: Ji-Eun Lee, Young Sook Kim
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Functional Foods
Subjects:
Apigenin
Pemphigus vulgaris
Autoimmune skin disease
Desmoglein3
p38 MAPK
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624005061

Internet

http://www.sciencedirect.com/science/article/pii/S1756464624005061

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