Simultaneous Transplantation of Fetal Ventral Mesencephalic Tissue and Encapsulated Genetically Modified Cells Releasing GDNF in a Hemi-Parkinsonian Rat Model of Parkinson’s Disease
Transplantation of fetal ventral mesencephalic (VM) neurons for Parkinson’s disease (PD) is limited by poor survival and suboptimal integration of grafted tissue into the host brain. In a 6-hydroxydopamine rat model of PD, we investigated the feasibility of simultaneous transplantation of rat fetal...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2017-09-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.1177/0963689717721202 |