Development and Validation of a HPLC-MS/MS Method for Simultaneous Determination of Twelve Bioactive Compounds in Epimedium: Application to a Pharmacokinetic Study in Rats

Development and Validation of a HPLC-MS/MS Method for Simultaneous Determination of Twelve Bioactive Compounds in Epimedium: Application to a Pharmacokinetic Study in Rats

A rapid and reliable HPLC-MS/MS method has been developed and validated for the simultaneous quantification of twelve bioactive compounds (baohuoside II, baohuoside I, sagittatoside A, sagittatoside B, magnoflorine, epimedin A, epimedin B, epimedin C, chlorogenic acid, neochlorogenic acid, cryptochl...

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Bibliographic Details
Main Authors: Mengjie Sun, Yanwei Yin, Juan Wei, Xiaopeng Chen, Huizi Ouyang, Yanxu Chang, Xiumei Gao, Jun He
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Molecules
Subjects:
Epimedium extract
pharmacokinetics
HPLC-MS/MS
rat plasma
Online Access:http://www.mdpi.com/1420-3049/23/6/1322

Internet

http://www.mdpi.com/1420-3049/23/6/1322

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