Sexual Dimorphism of Dexamethasone as a Prophylactic Treatment in Pathologies Associated With Acute Hypobaric Hypoxia Exposure

Sexual Dimorphism of Dexamethasone as a Prophylactic Treatment in Pathologies Associated With Acute Hypobaric Hypoxia Exposure

Dexamethasone can be taken prophylactically to prevent hypobaric hypoxia-associated disorders of high-altitude. While dexamethasone-mediated protection against high-altitude disorders has been clinically evaluated, detailed sex-based mechanistic insights have not been explored. As part of our India-...

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Bibliographic Details
Main Authors: Neha Chanana, Tsering Palmo, Kavita Sharma, Rahul Kumar, Bhushan Shah, Sudhanshu Mahajan, Girish M. Palleda, Mohit D. Gupta, Ritushree Kukreti, Mohammad Faruq, Tashi Thinlas, Brian B. Graham, Qadar Pasha
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
high-altitude
acute mountain sickness
pulmonary hypertension
dexamethasone
sexual dimorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.873867/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.873867/full

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