15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells

15-Deoxy-Delta-12,14-prostaglandin J2 modulates pro-labour and pro-inflammatory responses in human myocytes, vaginal and amnion epithelial cells

BackgroundPrematurity is the leading cause of childhood death under the age of five. The aetiology of preterm birth is multifactorial; however, inflammation and infection are the most common causal factors, supporting a potential role for immunomodulation as a therapeutic strategy. 15-Deoxy-Delta-12...

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Bibliographic Details
Main Authors: Zahirrah BM. Rasheed, Yun S. Lee, Sung H. Kim, Tg Teoh, David A. MacIntyre, Phillip R. Bennett, Lynne Sykes
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
nuclear factor - kappa B (NF - κB)
activator protein (AP)-1
inflammation
cytokines
prostaglandins
preterm labour (PTL)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.983924/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.983924/full

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