Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3

Light-Mediated Inhibition of Colonic Smooth Muscle Constriction and Colonic Motility via Opsin 3

Opsin photoreceptors outside of the central nervous system have been shown to mediate smooth muscle photorelaxation in several organs. We hypothesized that opsin receptor activation in the colon would have a similar effect and influence colonic motility. We detected Opsin 3 (OPN3) protein expression...

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Bibliographic Details
Main Authors: William Dan, Ga Hyun Park, Shruti Vemaraju, Amy D. Wu, Kristina Perez, Meenakshi Rao, Dan E. Berkowitz, Richard A. Lang, Peter D. Yim
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Physiology
Subjects:
colon
motility
opsin
relaxation
neuron
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.744294/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.744294/full

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