Immune cell dynamics deconvoluted by single-cell RNA sequencing in normothermic machine perfusion of the liver

Abstract Normothermic machine perfusion (NMP) has emerged as an innovative organ preservation technique. Developing an understanding for the donor organ immune cell composition and its dynamic changes during NMP is essential. We aimed for a comprehensive characterization of immune cell (sub)populati...

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Bibliographic Details
Main Authors: T. Hautz, S. Salcher, M. Fodor, G. Sturm, S. Ebner, A. Mair, M. Trebo, G. Untergasser, S. Sopper, B. Cardini, A. Martowicz, J. Hofmann, S. Daum, M. Kalb, T. Resch, F. Krendl, A. Weissenbacher, G. Otarashvili, P. Obrist, B. Zelger, D. Öfner, Z. Trajanoski, J. Troppmair, R. Oberhuber, A. Pircher, D. Wolf, S. Schneeberger
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37674-8