Inhibition of acyl-CoA binding protein (ACBP) by means of a GABAARγ2-derived peptide
Abstract Acyl-CoA binding protein (ACBP) encoded by diazepam binding inhibitor (DBI) is an extracellular inhibitor of autophagy acting on the gamma-aminobutyric acid A receptor (GABAAR) γ2 subunit (GABAARγ2). Here, we show that lipoanabolic diets cause an upregulation of GABAARγ2 protein in liver he...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2024-04-01
|
Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-024-06633-6 |