Interaction between peripheral blood mononuclear cells and Trypanosoma cruzi-infected adipocytes: implications for treatment failure and induction of immunomodulatory mechanisms in adipose tissue

Interaction between peripheral blood mononuclear cells and Trypanosoma cruzi-infected adipocytes: implications for treatment failure and induction of immunomodulatory mechanisms in adipose tissue

Background/IntroductionAdipose tissue (AT) has been highlighted as a promising reservoir of infection for viruses, bacteria and parasites. Among them is Trypanosoma cruzi, which causes Chagas disease. The recommended treatment for the disease in Brazil is Benznidazole (BZ). However, its efficacy may...

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Bibliographic Details
Main Authors: Leyllane Rafael Moreira, Ana Carla Silva, Cíntia Nascimento da Costa-Oliveira, Claudeir Dias da Silva-Júnior, Kamila Kássia dos Santos Oliveira, Diego José Lira Torres, Michelle D. Barros, Michelle Christiane d. S. Rabello, Virginia Maria Barros de Lorena
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
adipose tissue
immunomodulation
Trypanosoma cruzi
cytokine
chemokine
adipokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1280877/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1280877/full

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