Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth

Summary: As a common complication of diabetes, the pathogenesis of diabetic peripheral neuropathy (DPN) is closely related to high glucose but has not been clarified. Exosomes can mediate crosstalk between Schwann cells (SC) and neurons in the peripheral nerve. Herein, we found that miR-21 in serum...

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Bibliographic Details
Main Authors: Yu-pu Liu, Ming-yue Tian, Yi-duo Yang, Han Li, Tian-tian Zhao, Jing Zhu, Fang-fang Mou, Guo-hong Cui, Hai-dong Guo, Shui-jin Shao
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222014134